Q&A: Colossal Biosciences
Meet the CEO behind the company bringing ancient animals back from extinction
Ben Lamm is the CEO and co-founder of Colossal Biosciences, a Dallas-based biotechnology and genetic-engineering company working to bring back extinct species. Following the so-called return of the dire wolf – the first of its kind in more than 10,000 years – Lamm spoke to Monocle about the role of synthetic biology in conservation and the importance of journalism for science.
Why did you bring back the dire wolf?
Because we can and because the same technologies can help to save species on the brink. There are only 15 red wolves left in the wild. We have actually created more red wolves than dire wolves but people have naturally focused on the Game of Thrones aspect [dire wolves feature in the series]. This isn’t just about bringing back extinct animals. It’s also about protecting what we still have. That’s why we created a $50m (€44m) foundation dedicated to conservation. All of our technology is free for conservationists. People are busy: they hear “dire wolves” and don’t dig deeper. But we’re not ignoring endangered species.
There has been some debate over whether this is actually a dire wolf. Were you surprised by this reaction?
Honestly, yes. Our team did something that has never been done before. We used the ancient DNA of dire wolves to edit the biology of their closest living relatives: the grey wolf. That’s monumental. Yet some people wanted to focus solely on taxonomy. There are more than 30 ways to define a species. Call it a dire wolf, a Colossal dire wolf or the most genetically modified wolf ever – whatever works. But don’t lose sight of the science or the effect on conservation. That’s what matters.
So what’s next?
The mammoth is still on track for 2028. The dodo is close too; we’re working to jump over the last biological hurdle now. We also plan to grow the number of dire wolves, adding between five and eight more to the pack. Perhaps one day we’ll rewild them with the approval of our indigenous partners.
‘Time’ put your wolves on the cover. What did that mean to you?
It was huge. As a child, my grandfather had a mock Time cover with a photo of the two of us on it, so this felt deeply personal. It was a bit of a full-circle moment. More importantly, it showed that the science is being taken seriously.